Targeting a relapse causing protein to treat childhood acute myeloid leukaemia
Investigating how a protein that causes relapse in acute myeloid leukaemia interacts with the genetic code, and whether these interactions could be prevented.
We have been funding expert research since 2016, aiming to ensure that every child and young person has a safe and effective treatment for their cancer, and that they can live long and happy lives post-treatment.
Investigating how a protein that causes relapse in acute myeloid leukaemia interacts with the genetic code, and whether these interactions could be prevented.
Looking at how nanoparticles could improve drug delivery and reduce toxicity for young cancer patients.
Looking at the early stages of leukaemia that develops after treatment for other cancers to find out what changes occur and how to fight it.
Modifying current immunotherapy so that it doesn't cause damage to nerve cells and instead targets three molecules to help kill neuroblastoma cells more effectively.
Using two drugs to prevent an essential Wilms tumour protein interacting with a growth-promoting protein, and testing this treatment in patient samples.
Using Burkitt lymphoma models to find essential survival genes to target for therapy.
Testing whether treatment could be safely reduced for children with germinoma brain tumours
Investigating how cancer cells can keep dividing and why this makes it harder to treat.
Using anti-depressants to prevent the body's immune system from fighting immunotherapy treatments.